Correlation between renal parenchymal thickness and EGFR in chronic kidney disease
Author(s): Dr. Vinod S, Dr. Jagadeep MR and Dr. Abdul Eksana AS
Abstract: Objective: A prospective study developed to determine the relationship between renal parenchymal thickness and glomerular filtration rate in patients with chronic kidney disease.Materials and Methods: From June 2019 to June 2020, 50 patients were clinically diagnosed with chronic kidney disease. The lowest serum creatinine was used for calculation of the glomerular filtration rate (eGFR) using the Modification of Diet in Renal Disease Study (MDRD) equations. The ultrasounds were done by a single radiologist and reviewed by 2 consultants. The renal parenchymal thickness was measured in the longitudinal from the renal sinus to the outer renal cortical margin at upper, mid and lower levels of each kidney and the mean value was estimated for each kidney. Statistical Package for Social Science (SPSS 20.0) version used for data analysis and an unpaired test was applied to find the statistical significance. Pearson correlation test applied to find the correlation between the variables. A P value less than 0.05 (p<0.05) was considered statistically significant at 95% confidence interval.Results: US findings revealed that the mean renal parenchymal thickness was 11.2±3.01 mm. 68% (Right) and 70% (Left) of cases demonstrated grade II echogenicity followed by grade III parenchymal echogenicity with poor cortico-medullary differentiation of 14% cases on right side and 12% on left side. Mean serum creatinine was 3.9±2.2. The mean eGFR was 22.8±15.1 using MDRD formula. There was a statistically significant relationship between renal parenchymal thickness and eGFR using MDRD formula (p=0.002).Conclusion: Renal parenchymal thickness measured on ultrasound appears closely related to the eGFR using MDRD formula. Therefore, renal parenchymal thickness should be considered in routine ultrasound reporting for the patients with chronic kidney disease who are not on dialysis.
Dr. Vinod S, Dr. Jagadeep MR, Dr. Abdul Eksana AS. Correlation between renal parenchymal thickness and EGFR in chronic kidney disease. J Case Rep Sci Images 2020;2(2):12-16. DOI: 10.22271/27080056.2020.v2.i2a.19
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