P-ISSN: 2708-0056, E-ISSN: 2708-0064
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Journal of Case Reports and Scientific Images
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2021, Vol. 3, Issue 1, Part A

Low flow anesthesia while using desflurane vs isoflurane: A prospective randomized clinical comparison study

Author(s): Dr. Kalyan Nayak Banavathu and Dr. Fathima Ghazala

Abstract: Aim: To use equilibration time to compare the properties of desflurane and isoflurane during low flow anesthesia.Material and Methods: The Department of Anesthesia at Gandhi Hospital in Hyderabad, India, conducted this prospective research. In this research, 100 healthy patients of either sex who were scheduled for routine surgery and had hemoglobin levels more than 10 g/dL and American Society of Anesthesiologists (ASA) physical status I or II were included. Patients were divided into two groups at random. Desflurane was administered as the inhalational anesthetic with minimum flow anesthesia to Group I (n=50). Isoflurane was administered to Group II (n=50) along with minimum flow anesthesia.Results: There were 100 adult patients investigated. Two groups of 50 patients each were created by randomly dividing the groups. The average amount of time needed to equilibrate the volatile anesthetic agent was 5.23 1.63 min in the desflurane group and 17.011 9.64 min in the isoflurane group. This difference was statistically significant (P 0.001). Desflurane's mean end-tidal concentrations (in kPa) were 4.68 0.80, 4.78 0.62, 4.38 0.61, and 4.15 0.62 at 5, 20, 60, and 120 minutes, respectively. At 5-, 20-, and 120-minute intervals, respectively, the variation in the isoflurane group was 0.77 0.17, 0.93 0.17, 0.73 0.19, and 0.74 0.19. When any of the systems had reached equilibration, the uptake of nitrous oxide was at least 80%.Conclusion: We came to the conclusion that minimal flow anesthesia may be used more effectively with the availability of drugs like desflurane, resulting in less anesthetic gas drift, a clearer recovery, and less operating room pollution.

DOI: 10.22271/27080056.2021.v3.i1a.59

Pages: 21-24 | Views: 286 | Downloads: 126

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How to cite this article:
Dr. Kalyan Nayak Banavathu, Dr. Fathima Ghazala. Low flow anesthesia while using desflurane vs isoflurane: A prospective randomized clinical comparison study. J Case Rep Sci Images 2021;3(1):21-24. DOI: 10.22271/27080056.2021.v3.i1a.59

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