Printed Journal | Refereed Journal | Peer Reviewed Journal
2021, Vol. 3, Issue 2, Part A
False macrocytosis in chronic lymphocytic leukemia and how we can correct it
Author(s): Moueden Mohamed Amine, Messaoudi Reda, Seghier Fatima and Dr. G Ramakrishna Reddy
Abstract: Aim: To present a case report of CLL, with a false macrocytosis caused by an important lymphocytosis and to demonstrate how we were able to detect it and our action to correct it. Methodology: When we have double population RBC histogram we have to use another parameter is the red blood cells most frequent volume (R-MFV) that defines the peak of the curve and fits the MCV in normal distribution. Results: CBC revealed leucocytosis (60×109/L), moderate normochromic anaemia (haemoglobin of 11.9 g/dL, MCV of 125 fl, In our case R-MFV is of 107 fl. The macrocytosis is still present; but would not be expected to reach 125 fl. It is also necessary to recalculate the parameters which depend on the MCV. Liver laboratory tests are abnormal in relation to the liver failure. This explains the mild macrocytosis observed even after correction of MCV. Conclusion: Pronounced leukocytosis can lead to overestimation of the MCV, especially in chronic lymphoid leukemia, therefore we must be careful when we interpret the parameters of complete blood count.
DOI: 10.22271/27080056.2021.v3.i2a.31
Pages: 12-13 | Views: 1281 | Downloads: 627
Download Full Article: Click Here
How to cite this article:
Moueden Mohamed Amine, Messaoudi Reda, Seghier Fatima, Dr. G Ramakrishna Reddy. False macrocytosis in chronic lymphocytic leukemia and how we can correct it. J Case Rep Sci Images 2021;3(2):12-13. DOI: 10.22271/27080056.2021.v3.i2a.31
Related Journal Subscription
Related Links
Journal of Case Reports and Scientific Images
This is an open access journal which means that all content is freely available without charge to the user or his/her institution. Users are allowed to read, download, copy, distribute, print, search, or link to the full texts of the articles in this journal without asking prior permission from the publisher or the author. This is in accordance with the Budapest Open Access Initiative (BOAI) definition of open access.
The articles in Journal of Case Reports and Scientific Images are open access articles licensed under the terms of the Creative Commons Attribution Non-Commercial License (https://creativecommons.org/licenses/by-nc-sa/3.0/) which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited.
Copyright © 2024 Journal of Case Reports and Scientific Images All Rights Reserved. Subject to change without notice from or liability to Journal of Case Reports and Scientific Images.
Contact Information
Any correspondence, queries or additional requests for information on the manuscript submission process should be sent to the Journal of Case Reports and Scientific Images editorial office as follows:
Address: 1st Floor, Block C, Metropolitan Park, 8 Hillside Road, Parktown, Johannesburg, 2196, South Africa
Email: allcasereports@gmail.com
